How do I know if Mytesi is right for me?

Mytesi is a prescription medicine that helps relieve symptoms of diarrhea not caused by an infection in adults living with HIV/AIDS on antiretroviral therapy (ART). Ask your doctor if Mytesi is an appropriate choice to help relieve your diarrhea. Get the discussion guide.

Will Mytesi cause any drug interactions with my ART?

In clinical studies, Mytesi did not show any clinically meaningful drug-drug interactions. It will not affect how well your ART works. See full prescribing information.

Will Mytesi affect my HIV viral load or CD4 counts?

No. In clinical studies, Mytesi did not affect HIV viral load or CD4 counts. See full prescribing information.

Will I get constipated if I take Mytesi?

Mytesi is not likely to make you constipated. Many other prescription and OTC diarrhea medicines work by slowing down your gastrointestinal (GI) tract, which can cause constipation. Mytesi is a non-opioid that works differently by balancing the amount of water and salts in the GI tract and does not result in the diarrhea-constipation cycle often caused by some other medicines. Learn more about how Mytesi works.

What are the most common side effects of Mytesi?

The most common side effects were upper respiratory tract infection (6%), bronchitis (4%), cough (4%), flatulence (3%), and increased bilirubin (3%). In clinical studies, people taking Mytesi had similar side effects to those people taking placebo. See full prescribing information.

What is the right way to take Mytesi?

The FDA has approved a recommended adult dosage of Mytesi is 125 mg taken orally two times a day, with or without food. Mytesi tablets should not be crushed or chewed. See full prescribing information.

How can I get Mytesi?

Mytesi is a prescription medication. Ask your doctor if Mytesi is right for you. Our goal is to ensure that each person for whom Mytesi is medically appropriate is able to access Mytesi. Learn about our patient support programs.

How does Mytesi work to resolve my diarrhea?

Mytesi works to restore the balance of salts and water in your GI tract, leading to a change in stool consistency from watery to formed stools, resulting in symptomatic relief and a decrease in diarrhea. Learn more about how Mytesi works.

How is Mytesi made?

Crofelemer, the active ingredient in Mytesi, comes from the red bark sap of the Croton lechleri tree that grows in the Amazon rainforest. The sap is sustainably harvested and shipped to a manufacturing facility where it undergoes a complex purification process that results in crofelemer, which is then converted into Mytesi tablets. Learn more about how Mytesi is made Learn how Mytesi is made.