Graphic illustration: 1 in 5 people living HIV has diarrhea

Mytesi is indicated for:

People living with HIV/AIDS

Who take antiretroviral therapy (ART)

Who have noninfectious diarrhea

Mytesi is a medicine to treat diarrhea in adults living with HIV on ART who have diarrhea not caused by an infection.

This kind of diarrhea is called noninfectious diarrhea. It is not caused by an infection from bacteria, a virus, or a parasite. In people living with HIV/AIDS, this kind of diarrhea may be a side effect of ART. It can also be caused by the effects of HIV on the lining of the intestines. No matter its cause, the result is the same—diarrhea that can disrupt your life.

Mytesi is not likely to cause constipation

Over 98% of people on Mytesi in clinical studies did not report any constipation

Compared with people taking placebo, people taking Mytesi had the same number of side effects or even fewer. Learn how Mytesi works.


  • Did not cause any clinically relevant drug interactions in clinical studies. This means Mytesi did not change the way other medicines worked and other medicines did not effect Mytesi. Learn about Mytesi studies.
  • Will not change your viral load or CD4 counts
  • Comes from a tree that grows in the Amazon Rainforest. Mytesi does not come from man-made chemicals. Learn how Mytesi is made.
constipation cycle

If you have diarrhea, you’re certainly not alone…but maybe Mytesi can help.
Ask your health care provider.

How do you take Mytesi?

Mytesi comes as a 125-mg delayed-release tablet.

Take 1 Mytesi tablet 2 times each day.
You can take it with or without food.
Mytesi tablets should not be crushed or chewed. Tablets should be swallowed whole.

Be sure to take all your other medicines as directed by your doctor.
Mytesi will not interfere with the way they work.