How Does Mytesi Work?

How Does Mytesi Work?

What you may expect ​from taking Mytesi

HIV-related diarrhea results from an imbalance of salts and water in the gastrointestinal (GI) tract, or gut. Mytesi works by restoring the balance of salts and water in the gut, normalizing the flow of water and resulting in less watery diarrhea.1

  • Normal

    Chloride ion (Cl–) channels in the gastrointestinal (GI) tract maintain a balance of salts—including chloride ions—and water that allows normal stool formation.

  • Diarrhea

    Ion channels that don’t work properly lead to too much salt and water within the gut, disrupting the normal balance and resulting in diarrhea.

  • Starting Mytesi

    Mytesi restores the balance of salts and water in the GI tract by normalizing improperly functioning chloride ion (Cl–) channels.

  • Long-term Results

    After 3-4 weeks, Mytesi can reduce the severity of watery bowel movements and provide sustained long-term relief.1 In nonclincal studies, crofelemer, the active ingredient in Mytesi, does not slow down gut motility and is therefore less likely to cause constipation.

Mytesi works differently than other treatments for diarrhea. With Mytesi, it’s about water flow.

Mytesi offers advantages

In clinical studies, Mytesi did not show any clinically meaningful interactions with other medicines, meaning it is unlikely to affect how well your antiretroviral therapy (ART) works.

In clinical studies, Mytesi did not affect HIV viral load or CD4 counts.

Help address the diarrhea-constipation cycle

Help address the diarrhea-constipation cycle

Over 98% of people taking Mytesi in clinical studies did not report any constipation.1

Mytesi provides symptomatic relief of
noninfectious HIV-related diarrhea.

Mytesi provides symptomatic relief of noninfectious HIV-related diarrhea.

View Clinical Results

Reference: 1. Mytesi [package insert]. San Francisco, CA: Napo Pharmaceuticals Inc; 2018.